pentobarbital will lessen the extent or influence of voriconazole by affecting hepatic enzyme CYP2C9/10 metabolism. Small/Importance Not known.

Barbiturates can induce hepatic microsomal enzymes leading to increased metabolism and reduced anticoagulant reaction of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); patients stabilized on anticoagulant therapy may need dosage changes if barbiturates are additional to or withdrawn from their dosage program

pentobarbital will lessen the level or result of ixabepilone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

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pentobarbital will minimize the extent or impact of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will lessen the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.

pentobarbital will lower the level or result of fesoterodine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital will lower the extent or effect of etravirine by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.

pentobarbital will reduce the level or effect of lapatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will decrease the extent or impact of felodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital more info will lessen the level or impact of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers may result in diminished serum concentrations and lack of antimalarial efficacy

pentobarbital will decrease the level or result of rabeprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.

Contraindicated (one)pentobarbital will reduce the level or outcome of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the extent or impact of ramelteon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.